Proven Research

A Proven, Research-Backed Sleep Support Formula

Modern research on traditional herbs commonly used in sleep support formulas, particularly White Peony Root (Bai Shao) and Goldthread Rhizome (Huang Lian), has explored their effects on neurotransmitter regulation, antioxidant activity, nervous system balance, and overall wellness. Research published in the Chinese Journal of Integrative Medicine has examined herbal combinations traditionally used for insomnia and identified combinations containing White Peony Root and Goldthread Rhizome among those associated with positive clinical outcomes for improving sleep quality.

Additional research published in Phytomedicine and the Journal of Ethnopharmacology has investigated the pharmacological activities of White Peony Root, including its major active compound paeoniflorin, for its role in supporting nervous system balance and healthy physiological responses to stress. Comprehensive reviews published on Goldthread Rhizome (Coptis chinensis) have also examined its bioactive alkaloids, including berberine, and their antioxidant, neuroprotective, and physiological regulatory properties.

From a Traditional Chinese Medicine perspective, restful sleep depends on the harmonious relationship between the Heart and Kidney systems. When Heart Fire is calmed, Kidney Yin is supported, and the Shen (Mind) is nourished, the body is traditionally believed to experience more peaceful sleep, reduced restlessness, and a calmer emotional state.

Research References

Patterns of Herbal Combination for the Treatment of Insomnia Commonly Employed by Highly Experienced Chinese Medicine Physicians (Chinese Journal of Integrative Medicine)
https://link.springer.com/article/10.1007/s11655-011-0841-9

White Peony (Paeonia lactiflora Pall.): A Review of Its Phytochemistry and Pharmacology (Journal of Ethnopharmacology)
https://www.sciencedirect.com/science/article/pii/S0378874115302614

Coptidis Rhizoma: A Comprehensive Review of Its Traditional Uses, Phytochemistry, Pharmacology and Toxicology (Phytomedicine)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6461078/